Introduction to Ethics in Medicine

Matthias Girke

Last update: 07.09.2020

Assessments and therapeutic measures used in medical and therapeutic practice are determined by the values and basic assumptions of one’s view of the human being. Elderly patients in intensive care challenge us in our therapeutic decision-making process, while cancer patients are faced with decisions regarding the often limited effectiveness of the systemic therapy recommended to them. Therapeutically relevant questions are not just concerned with what is “effective” and potentially “feasible”, but with what is beneficial for the patient, i.e. with what he or she considers to be “good”. The three pillars of David Sacket’s evidence-based medicine – external evidence, individual expertise and patient preference – only become complete when a positive patient benefit assessment is included.
Basic concepts of illness and recovery, the patient-doctor relationship and ethical decision-making all depend on the doctor’s view of the human being and are weighted against and determined by it.

Research news

Case series: Topical application of Viscum album extract in keratinocyte carcinomas shows remissions 
A retrospective case series examined the safety and clinical effects of topical application of 10% lipophilic Viscum album extract (VALE) in individual cases of cutaneous squamous cell carcinoma (cSCC), basal cell carcinoma (BCC) and actinic keratosis (AK). The study population consisted of 55 patients with 74 skin lesions. Risk factors, concomitant therapies and diseases, adverse drug reactions to VALE and other relevant information were documented. As a result, the clinical response rate was 78% for cSCC, 70% for BCC and 71% for AK. The complete remission rates for individual lesions were 56% for cSCC, 35% for BCC and 15% for AK. Overall, the results suggest that VALE is a safe and tolerable extract, and complete and partial remissions of ceratinocyte carcinomas were observed with its use. The article is published in Complementary Medicine Research
https://doi.org/10.1159/000537979.


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