Ascites

Marion Debus

Last update: 15.01.2019

Ascites is an accumulation of excess fluid in the abdominal cavity that has fallen out of the circulation processes of the life organization. The peritoneum is a “fluid-breathing” organ where fluid is constantly being formed and resorbed on its 2m² surface between the visceral and parietal peritoneum. The parietal peritoneum is very sensitive to pain and close to consciousness, which is noticed during punctures; it thus shows a relationship to the person’s capacity for sensation and consciousness (astral organization). The visceral peritoneum, which is directly adjacent to the abdominal organs, contains no pain fibers and is more related to the unconscious life organization. Just as each inhalation resembles a quiet awakening, and each exhalation a subtle tendency to fall asleep, in the abdominal cavity liquid secretion and resorption rhythmically oscillate between the two peritoneal layers and create the wafer-thin liquid film. It is through this process that the layers elastically adapt to the strongly changing volume of the abdomen.

In ascites formation, which most frequently occurs as a result of hardening processes (often in the context of peritoneal carcinosis or metastatic liver disease), there is a disturbance in the balance between production and reuptake of fluid. The accumulation of fluid indicates an insufficient activity of the life organization, which is no longer permeated by the “breathing” of the sentient organization. The liquid follows gravity and is deposited in a “third space”. It is no longer sufficiently integrated into the patient’s life processes.

The place of accumulation feels heavy and cool to the patient, which is also related to inadequate intervention by the “I”-organization. Ascites can exert enormous pressure on adjacent organs, resulting in loss of appetite, nausea, vomiting, reduced peristalsis, meteorism and constipation.

The treatment of ascites accordingly requires a multimodal approach, which, in addition to (not very promising) diuretic therapy and the possibly necessary relieving punctures, would aim to support the life organization, sentient organization and “I” activity.

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Mistletoe therapy in addition to standard immunotherapy in patients with non-small-cell lung cancer indicates improved survival rates 
Immunotherapy with PD-1/PD-L1 inhibitors has significantly improved the survival rates of patients with metastatic non-small-cell lung cancer (NSCLC). Results of a real-world data study (RWD) investigating the addition of Viscum album L. (VA) to chemotherapy have shown an association with improved survival in patients with NSCLC - regardless of age, degree of metastasis, performance status, lifestyle or oncological treatment. The mechanisms may include synergistic modulations of the immune response by PD-1/PD-L1 inhibitors and VA. However, the results should be taken with caution due to the observational and non-randomised study design. The study has been published open access in Cancers
https://doi.org/10.3390/cancers16081609.


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